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Ligand · O92

O92 · 3-amino-6-{4-chloro-3-[(2,3-difluorophenyl)sulfamoyl]phenyl}-N-methylpyrazine-2-carboxamide

O92, 3-amino-6-{4-chloro-3-[(2,3-difluorophenyl)sulfamoyl]phenyl}-N-methylpyrazine-2-carboxamide (C18 H14 Cl F2 N5 O3 S, 453.9 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its…

Component
O92
Formula
C18 H14 Cl F2 N5 O3 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

O92 in 2 structures; the first of them:

  • 4ANW · Complexes of PI3Kgamma with isoform selective inhibitors. · O92 A1189 · binds MET804, ALA805, SER806, PRO810, TRP812, ILE831, LYS833, ASP841 and 12 more
  • 4ANW · Complexes of PI3KGAMMA with isoform selective inhibitors. · O92 A1189 · binds MET804, ALA805, SER806, PRO810, TRP812, ILE831, LYS833, ASP841 and 12 more

Residues it binds most

ILE 2, ASP 2, ALA 2, LYS 2, MET 2, GLU 2, PRO 2, SER 2, THR 2, TRP 2 (residue and the binding sites it lines).

Found with

  • SO4 · Sulfate ion

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