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Ligand · O7S

O7S · (3r,4r,5e,10e,12e,14s,16r,26ar)-16-fluoro-14-hydroxy-12-methyl-3-(propan-2-yl)-4-(prop-2-en-1-yl)-3,4,8,9, 14,15,16,17,24,25,26,26A-dodecahydro-1H,7H,22H-21,18-(azeno)pyrrolo[2,1-C][1,8,4, 19]dioxadiazacyclotetracosine-1,7,22-trione

O7S, (3r,4r,5e,10e,12e,14s,16r,26ar)-16-fluoro-14-hydroxy-12-methyl-3-(propan-2-yl)-4-(prop-2-en-1-yl)-3,4,8,9, 14,15,16,17,24,25,26,26A-dodecahydro-1H,7H,22H-21,18-(azeno)pyrrolo[2,1-C][1,8,4, 19]dioxadiazacyclotetracosine-1,7,22-trione…

Component
O7S
Formula
C30 H40 F N3 O6
Class
ligand
Structures
4
PDB entries
3

Binding sites

O7S in 4 structures; the first of them:

  • 6PC6 · E. coli 50S ribosome bound to compound 47 · O7S I3001 · binds G2061, A2062, C2063, A2451, C2452, 2MA2503, PSU2504, G2505 and 3 more
  • 6PC6 · E. COLI 50S ribosome bound to compound 47 · O7S I3001 · binds G2061, A2062, C2063, A2451, C2452, 2MA2503, PSU2504, G2505 and 3 more
  • 6WYV · E. COLI 50S ribosome bound to compounds 47 and VS1 · O7S I3001 · binds G2061, A2062, C2063, A2451, C2452, 2MA2503, PSU2504, G2505 and 3 more
  • 6X3C · Crystal structure of streptogramin a acetyltransferase vata from staphylococcus aureus in… · O7S A302 · binds TYR59, GLY84, ALA85, ASN86, HIS87, HIS97, LEU98, MET107 and 8 more

Residues it binds most

LEU 6, TYR 6, ASN 6, HIS 6, U 3, A 3, ALA 6, ASP 6, C 3, G 3 (residue and the binding sites it lines).

Found with

  • SXA · Thioacetic acid S-{2-[3-(2-hydroxy-3,3-dimethyl-4-phosphonooxy-butyrylamino)-propionylamino]-ethyl} ester
  • MG · Magnesium ion
  • CL · Chloride ion
  • PO4 · Phosphate ion
  • SO4 · Sulfate ion

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