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Ligand · O72

O72 · 1,7-naphthyridin-8-amine

O72, 1,7-naphthyridin-8-amine (C8 H7 N3, 145.2 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found with it.

Component
O72
Formula
C8 H7 N3
Class
ligand
Structures
4
PDB entries
2

Binding sites

O72 in 4 structures; the first of them:

  • 6Y2O · Crystal structure of the cAMP-dependent protein kinase A cocrystallized with… · O72 A406 · binds LEU49, VAL57, ALA70, VAL104, MET120, GLU121, TYR122, VAL123 and 3 more
  • 6YNR · Crystal structure of the cAMP-dependent protein kinase A in complex with… · O72 A403 · binds LEU49, VAL57, ALA70, VAL104, MET120, GLU121, TYR122, VAL123 and 3 more
  • 6Y2O · Crystal structure of the camp-dependent protein kinase a cocrystallized with… · O72 A406 · binds LEU49, VAL57, ALA70, VAL104, MET120, GLU121, TYR122, VAL123 and 3 more
  • 6YNR · Crystal structure of the camp-dependent protein kinase a in complex with… · O72 A403 · binds LEU49, VAL57, ALA70, VAL104, MET120, GLU121, TYR122, VAL123 and 3 more

Residues it binds most

VAL 4, LEU 4, ALA 4, GLU 4, MET 4, PHE 4, THR 4, TYR 4 (residue and the binding sites it lines).

Found with

  • DMS · Dimethyl sulfoxide
  • MPD · (4S)-2-methyl-2,4-pentanediol

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