GL1X · GenesisL1 explorer

Ligand · O47

O47 · 3-{2-[(E)-iminomethyl]-6-propylpyrimidin-4-yl}-N,N-dimethyl-5-(trifluoromethyl)benzamide

O47, 3-{2-[(E)-iminomethyl]-6-propylpyrimidin-4-yl}-N,N-dimethyl-5-(trifluoromethyl)benzamide (C18 H19 F3 N4 O, 364.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues…

Component
O47
Formula
C18 H19 F3 N4 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

O47 in 2 structures; the first of them:

  • 3O0U · Cathepsin K covalently bound to a cyano-pyrimidine inhibitor with improved selectivity… · O47 A216 · binds GLN19, CYS22, GLY23, SER24, CYS25, ASP61, GLY64, GLY65 and 9 more
  • 3O0U · Cathepsin K covalently bound to a cyano-pyrimidine inhibitor with improved selectivity… · O47 A216 · binds GLN19, CYS22, GLY23, SER24, CYS25, ASP61, GLY64, GLY65 and 9 more

Residues it binds most

GLY 2, ALA 2, CYS 2, LEU 2, ASN 2, ASP 2, GLN 2, HIS 2, MET 2, SER 2 (residue and the binding sites it lines).

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.