GL1X · GenesisL1 explorer

Ligand · NXR

NXR · N-[(2S)-1-{[(2R)-1-oxo-3-phenyl-1-{[3-(pyridin-3-yl) propyl]amino}propan-2-yl]sulfanyl}-3-phenylpropan-2-yl]pyridine-3-carboxamide

NXR, N-[(2S)-1-{[(2R)-1-oxo-3-phenyl-1-{[3-(pyridin-3-yl) propyl]amino}propan-2-yl]sulfanyl}-3-phenylpropan-2-yl]pyridine-3-carboxamide (C32 H34 N4 O2 S, 538.7 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB…

Component
NXR
Formula
C32 H34 N4 O2 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

NXR in 2 structures; the first of them:

  • 7UFE · Human CYP3A4 bound to an inhibitor · NXR A604 · binds ARG105, ARG106, PRO107, PHE108, SER119, ILE120, LEU210, LEU211 and 6 more
  • 7UFE · Human CYP3A4 bound to an inhibitor · NXR A604 · binds ARG105, ARG106, PHE108, SER119, LEU210, LEU211, PHE213, PHE241 and 4 more

Residues it binds most

PHE 4, ARG 4, ILE 4, LEU 4, ALA 4, SER 4, THR 4, PRO 2 (residue and the binding sites it lines).

Found with

  • HEM · Protoporphyrin IX containing Fe
  • GOL · Glycerol

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.