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Ligand · NUC

NUC · (2E)-3-[(7S)-7-amino-8-oxo-6,7,8,9-tetrahydro-5H-pyrido[2,3-b]azepin-3-yl]-N-methyl-N-[(3-methyl-1-benzofuran-2-yl)methyl]prop-2-enamide

NUC, (2E)-3-[(7S)-7-amino-8-oxo-6,7,8,9-tetrahydro-5H-pyrido[2,3-b]azepin-3-yl]-N-methyl-N-[(3-methyl-1-benzofuran-2-yl)methyl]prop-2-enamide (C23 H24 N4 O3, 404.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (2 PDB…

Component
NUC
Formula
C23 H24 N4 O3
Class
ligand
Structures
2
PDB entries
2

Binding sites

NUC in 2 structures; the first of them:

  • 7UMW · Crystal structure of E. Coli FabI in complex with NAD and Fabimycin… · NUC A302 · binds GLY93, PHE94, ALA95, GLY97, LEU100, TYR146, PRO154, ASN155 and 10 more
  • 7UMY · Crystal structure of Acinetobacter baumannii FabI in complex with NAD and Fabimycin… · NUC A302 · binds PHE96, ALA97, PRO98, ALA99, LEU102, TYR149, PRO157, ASN158 and 10 more

Residues it binds most

ALA 8, PRO 8, LEU 8, PHE 8, TYR 8, MET 8, SER 8, ASN 8, ILE 8, LYS 7 (residue and the binding sites it lines).

Found with

  • NAD · Nicotinamide-adenine-dinucleotide

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