Ligand · NPZ

NPZ · 1-methyl-3-naphthalen-2-yl-1H-pyrazolo[3,4-d]pyrimidin-4-amine

NPZ, 1-methyl-3-naphthalen-2-yl-1H-pyrazolo[3,4-d]pyrimidin-4-amine (C16 H13 N5, 275.3 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues it…

Component: NPZ
Formula: C16 H13 N5
Class: ligand
Structures: 2
PDB entries: 1

Binding sites

NPZ in 2 structures; the first of them:

3ENE · Complex of PI3K gamma with an inhibitor · NPZ A1 · binds TRP812, ILE831, LYS833, LEU838, ASP841, TYR867, ILE879, GLU880 and 6 more
3ENE · Complex of PI3K gamma with an inhibitor · NPZ A1 · binds TRP812, ILE831, LYS833, LEU838, ASP841, TYR867, ILE879, GLU880 and 6 more

Residues it binds most

ILE 2, ASP 2, GLU 2, LEU 2, LYS 2, MET 2, THR 2, TRP 2, TYR 2, VAL 2 (residue and the binding sites it lines).

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