GL1X · GenesisL1 explorer

Ligand · NHN

NHN · (6R,8S,11S)-11-cyclohexyl-N-(1-{[(2-{[(1S)-2-(dimethylamino)-2-oxo-1-phenylethyl]amino}-2-oxoethyl)amino](oxo)acetyl}butyl)-10,13-dioxo-2,5-dioxa-9,12-diazatricyclo[14.3.1.1~6,9~]henicosa-1(20),16,18-triene-8-carboxamide

NHN, (6R,8S,11S)-11-cyclohexyl-N-(1-{[(2-{[(1S)-2-(dimethylamino)-2-oxo-1-phenylethyl]amino}-2-oxoethyl)amino](oxo)acetyl}butyl)-10,13-dioxo-2,5-dioxa-9,12-diazatricyclo[14.3.1.1~6,9~]henicosa-1(20),16,18-triene-8-carboxamide (C42 H56 N6…

Component
NHN
Formula
C42 H56 N6 O9
Class
ligand
Structures
2
PDB entries
1

Binding sites

NHN in 2 structures; the first of them:

  • 2GVF · HCV NS3-4A protease domain complexed with a macrocyclic ketoamide inhibitor, SCH419021 · NHN A999 · binds THR40, GLN41, THR42, PHE43, VAL55, HIS57, ARG109, ARG123 and 13 more
  • 2GVF · HCV NS3-4A protease domain complexed with a macrocyclic ketoamide inhibitor, SCH419021 · NHN A999 · binds THR40, GLN41, THR42, PHE43, VAL55, HIS57, ARG109, ARG123 and 13 more

Residues it binds most

ARG 2, ALA 2, PHE 2, SER 2, THR 2, VAL 2, ASP 2, CYS 2, GLN 2, GLY 2 (residue and the binding sites it lines).

Found with

  • ZN · Zinc ion

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.