GL1X · GenesisL1 explorer

Ligand · NDZ

NDZ · (2R,3aR,6R,7R,7aR)-2-[(2S)-2-amino-2-carboxyethyl]-6,7-dihydroxyhexahydro-2H-furo[3,2-b]pyran-2-carboxylic acid

NDZ, (2R,3aR,6R,7R,7aR)-2-[(2S)-2-amino-2-carboxyethyl]-6,7-dihydroxyhexahydro-2H-furo[3,2-b]pyran-2-carboxylic acid (C11 H17 N O8, 291.3 g/mol), in the MolNFT structures on GenesisL1: bound in 6 records (3 PDB entries). Every binding site…

Component
NDZ
Formula
C11 H17 N O8
Class
ligand
Structures
6
PDB entries
3

Binding sites

NDZ in 6 structures; the first of them:

  • 2ZNU · Crystal structure of the ligand-binding core of the human ionotropic glutamate receptor… · NDZ A1 · binds GLU426, TYR429, TYR474, PRO501, LEU502, THR503, ARG508, VAL670 and 9 more
  • 3FV2 · Crystal structure of the human glutamate receptor, GluR5, ligand-binding core in complex… · NDZ A791 · binds GLU426, TYR474, PRO501, LEU502, THR503, ARG508, VAL670, GLY673 and 7 more
  • 3QXM · Crystal Structure of Human GluK2 Ligand-Binding Core in Complex with Novel Marine-Derived… · NDZ A301 · binds GLU409, TYR412, TYR457, PRO485, LEU486, ALA487, ARG492, VAL654 and 9 more
  • 2ZNU · Crystal structure of the ligand-binding core of the human ionotropic glutamate receptor… · NDZ A1 · binds GLU426, TYR429, TYR474, PRO501, LEU502, THR503, ARG508, VAL670 and 9 more
  • 3FV2 · Crystal structure of the human glutamate receptor, GLUR5, ligand- binding core in complex… · NDZ A791 · binds GLU426, TYR474, PRO501, LEU502, THR503, ARG508, VAL670, GLY673 and 7 more
  • 3QXM · Crystal structure of human GLUK2 ligand-binding core in complex with novel marine-derived… · NDZ A301 · binds GLU409, TYR412, TYR457, PRO485, LEU486, ALA487, ARG492, VAL654 and 9 more

Residues it binds most

TYR 10, GLU 10, THR 10, SER 6, MET 10, ARG 10, GLY 10, LEU 10, PRO 10, VAL 10 (residue and the binding sites it lines).

Found with

  • SO4 · Sulfate ion
  • BME · Beta-mercaptoethanol
  • GOL · Glycerol

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