Ligand · N7B
N7B · ~{N}-[2-(2-hydroxyethyloxy)-5-[4-[[1-(phenylmethyl) indazol-5-yl]amino]-7~{H}-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]propanamide
N7B, ~{N}-[2-(2-hydroxyethyloxy)-5-[4-[[1-(phenylmethyl) indazol-5-yl]amino]-7~{H}-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]propanamide (C31 H29 N7 O3, 547.6 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every…
- Component
- N7B
- Formula
- C31 H29 N7 O3
- Class
- ligand
- Structures
- 2
- PDB entries
- 1
Binding sites
N7B in 2 structures; the first of them:
- 6TFZ · Crystal Structure of EGFR T790M/V948R in Complex with Covalent Pyrrolopyrimidine 19 · N7B A1101 · binds LEU718, GLY719, SER720, PHE723, VAL726, ALA743, LYS745, MET766 and 18 more
- 6TFZ · Crystal structure of EGFR T790M/V948R in complex with covalent pyrrolopyrimidine 19 · N7B A1101 · binds LEU718, GLY719, SER720, PHE723, VAL726, ALA743, LYS745, MET766 and 17 more
Residues it binds most
LEU 4, MET 4, GLY 4, ASP 4, CYS 4, ARG 4, ALA 4, PHE 4, GLN 4, LYS 4 (residue and the binding sites it lines).
Found with
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