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Ligand · N5P

N5P · 1-{2-deoxy-5-O-[(R)-hydroxy{[(r)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-beta-D-erythro-pentofuranosyl}-5-nitro -1H-indole

N5P, 1-{2-deoxy-5-O-[(R)-hydroxy{[(r)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-beta-D-erythro-pentofuranosyl}-5-nitro -1H-indole (C13 H17 N2 O14 P3, 518.2 g/mol), in the MolNFT structures on GenesisL1: bound in 8 records (4 PDB…

Component
N5P
Formula
C13 H17 N2 O14 P3
Class
ligand
Structures
8
PDB entries
4

Binding sites

N5P in 8 structures; the first of them:

  • 2OYQ · Crystal structure of RB69 gp43 in complex with DNA with 5-NIMP opposite an abasic site… · N5P I704 · binds DC20, DG21, DG101
  • 2OZM · Crystal structure of RB69 gp43 in complex with DNA with 5-NITP opposite an abasic site… · N5P A905 · binds 3DR3, DC4, DDG14, ASP411, LEU412, THR413, SER414, LEU415 and 12 more
  • 3RSR · Crystal Structure of 5-NITP Inhibition of Yeast Ribonucleotide Reductase · N5P A841 · binds ASP226, SER227, ILE228, ILE231, ILE255, ARG256, ILE262, ALA263 and 3 more
  • 3T3F · Ternary Structure of the large fragment of Taq DNA polymerase bound to an abasic site and… · N5P A836 · binds ARG573, ASP610, TYR611, SER612, GLN613, ILE614, GLU615, HIS639 and 10 more
  • 2OYQ · Crystal structure of RB69 GP43 in complex with DNA with 5-nimp opposite an abasic site… · N5P I704 · binds DC20, DG21, DG101
  • 2OZM · Crystal structure of RB69 GP43 in complex with DNA with 5-nitp opposite an abasic site… · N5P A905 · binds 3DR3, DC4, DDG14, ASP411, LEU412, THR413, SER414, LEU415 and 12 more
  • 3RSR · Crystal structure of 5-nitp inhibition of yeast ribonucleotide reductase · N5P A841 · binds ASP226, SER227, ILE228, ILE231, ILE255, ARG256, ILE262, ALA263 and 3 more
  • 3T3F · Ternary structure of the large fragment of taq DNA polymerase bound to an abasic site and… · N5P A836 · binds ARG573, ASP610, TYR611, SER612, GLN613, ILE614, GLU615, HIS639 and 10 more

Residues it binds most

LYS 10, ARG 12, ASP 8, SER 8, DG 6, ILE 4, THR 8, TYR 6, ASN 8, GLY 8 (residue and the binding sites it lines).

Found with

  • MG · Magnesium ion
  • NA · Sodium ion
  • FMT · Formic acid
  • GOL · Glycerol

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