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Ligand · N1C

N1C · N1-cyclic inosine 5'-diphosphoribose

N1C, N1-cyclic inosine 5'-diphosphoribose (C15 H20 N4 O14 P2, 542.3 g/mol), in the MolNFT structures on GenesisL1: bound in 6 records (3 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the…

Component
N1C
Formula
C15 H20 N4 O14 P2
Class
ligand
Structures
6
PDB entries
3

Binding sites

N1C in 6 structures; the first of them:

  • 2PGJ · Catalysis associated conformational changes revealed by human cd38 complexed with a… · N1C A301 · binds LEU124, TRP125, SER126, ARG127, LYS129, LEU145, GLU146, ASP155 and 8 more
  • 2PGL · Catalysis associated conformational changes revealed by human CD38 complexed with a… · N1C A301 · binds LEU124, TRP125, SER126, ARG127, LYS129, LEU145, GLU146, ASP155 and 8 more
  • 3I9L · Crystal structure of ADP ribosyl cyclase complexed with N1-cIDPR · N1C A301 · binds TRP77, LEU97, GLU98, PHE128, ARG136, TRP140, SER144, PHE174
  • 2PGJ · Catalysis associated conformational changes revealed by human CD38 complexed with a… · N1C A301 · binds LEU124, TRP125, SER126, ARG127, LYS129, LEU145, GLU146, ASP155 and 8 more
  • 2PGL · Catalysis associated conformational changes revealed by human CD38 complexed with a… · N1C A301 · binds LEU124, TRP125, SER126, ARG127, LYS129, LEU145, GLU146, ASP155 and 8 more
  • 3I9L · Crystal structure of ADP ribosyl cyclase complexed with N1-cidpr · N1C A301 · binds TRP77, LEU97, GLU98, PHE128, ARG136, TRP140, SER144, PHE174

Residues it binds most

SER 6, PHE 6, TRP 6, LEU 6, GLU 6, ARG 6, ASP 4, LYS 4, THR 4, VAL 4 (residue and the binding sites it lines).

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