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Ligand · MZ1

MZ1 · N~2~-acetyl-N-[(1S,2R)-1-benzyl-2-hydroxy-3-{(2-thienylmethyl)[(2,4,5-trifluorophenyl)sulfonyl]amino}propyl]-L-alaninamide

MZ1, N~2~-acetyl-N-[(1S,2R)-1-benzyl-2-hydroxy-3-{(2-thienylmethyl)[(2,4,5-trifluorophenyl)sulfonyl]amino}propyl]-L-alaninamide (C26 H28 F3 N3 O5 S2, 583.6 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry).…

Component
MZ1
Formula
C26 H28 F3 N3 O5 S2
Class
ligand
Structures
2
PDB entries
1

Binding sites

MZ1 in 2 structures; the first of them:

  • 2QHY · Crystal Structure of protease inhibitor, MIT-1-AC86 in complex with wild type HIV-1… · MZ1 A200 · binds LEU23, ASP25, GLY27, ALA28, ASP29, VAL32, GLY48, GLY49 and 20 more
  • 2QHY · Crystal structure of protease inhibitor, mit-1-AC86 in complex with wild type HIV-1… · MZ1 A200 · binds LEU23, ASP25, GLY27, ALA28, ASP29, VAL32, GLY48, GLY49 and 20 more

Residues it binds most

GLY 2, ILE 2, ASP 2, VAL 2, LEU 2, ALA 2, PRO 2, ARG 2, THR 2 (residue and the binding sites it lines).

Found with

  • PO4 · Phosphate ion
  • ACT · Acetate ion

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