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Ligand · MXC

MXC · (2S,3R)-2-[(7-aminocarbonyl-2-methanoyl-indolizin-3-yl)amino]-4-aminocarbonyloxy-3-methyl-3-sulfino-butanoic acid

MXC, (2S,3R)-2-[(7-aminocarbonyl-2-methanoyl-indolizin-3-yl)amino]-4-aminocarbonyloxy-3-methyl-3-sulfino-butanoic acid (C16 H18 N4 O8 S, 426.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (2 PDB entries). Every binding…

Component
MXC
Formula
C16 H18 N4 O8 S
Class
ligand
Structures
2
PDB entries
2

Binding sites

MXC in 2 structures; the first of them:

  • 3FYZ · OXA-24 beta-lactamase complex with SA4-17 inhibitor · MXC A300 · binds ALA80, SER81, KCX84, THR111, TYR112, MET114, TRP115, SER128 and 8 more
  • 3MBZ · OXA-24 beta-lactamase complex soaked with 10mM SA4-17 inhibitor for 15min · MXC A276 · binds ALA80, SER81, KCX84, THR111, TYR112, TRP115, ALA126, LEU127 and 9 more

Residues it binds most

SER 2, TRP 2, ALA 2, LEU 2, MET 2, ARG 2, GLY 2, KCX 2, LYS 2, THR 2 (residue and the binding sites it lines).

Found with

  • SO4 · Sulfate ion
  • PG4 · Tetraethylene glycol

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