GL1X · GenesisL1 explorer

Ligand · MT4

MT4 · 5-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]-3-fluorophenyl}-2-[(4-fluorophenyl)amino]-3-methylpyrimidin-4(3H)-one

MT4, 5-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]-3-fluorophenyl}-2-[(4-fluorophenyl)amino]-3-methylpyrimidin-4(3H)-one (C28 H22 F2 N4 O4, 516.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site…

Component
MT4
Formula
C28 H22 F2 N4 O4
Class
ligand
Structures
2
PDB entries
1

Binding sites

MT4 in 2 structures; the first of them:

  • 3EFK · Structure of c-Met with pyrimidone inhibitor 50 · MT4 A1 · binds ILE1084, GLY1085, ARG1086, PHE1089, VAL1092, ALA1108, LYS1110, PHE1124 and 17 more
  • 3EFK · Structure of C-met with pyrimidone inhibitor 50 · MT4 A1 · binds ILE1084, GLY1085, ARG1086, PHE1089, VAL1092, ALA1108, LYS1110, PHE1124 and 17 more

Residues it binds most

GLY 4, LEU 4, MET 4, PHE 4, ALA 4, ILE 4, LYS 4, VAL 4, ASP 4, GLU 4 (residue and the binding sites it lines).

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.