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Ligand · MT3

MT3 · 2-benzyl-5-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]-3-fluorophenyl}-3-methylpyrimidin-4(3H)-one

MT3, 2-benzyl-5-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]-3-fluorophenyl}-3-methylpyrimidin-4(3H)-one (C29 H24 F N3 O4, 497.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues…

Component
MT3
Formula
C29 H24 F N3 O4
Class
ligand
Structures
2
PDB entries
1

Binding sites

MT3 in 2 structures; the first of them:

  • 3EFJ · Structure of c-Met with pyrimidone inhibitor 7 · MT3 A1 · binds ILE1084, GLY1085, PHE1089, VAL1092, ALA1108, LYS1110, LEU1112, PHE1124 and 16 more
  • 3EFJ · Structure of C-met with pyrimidone inhibitor 7 · MT3 A1 · binds ILE1084, GLY1085, PHE1089, VAL1092, ALA1108, LYS1110, LEU1112, PHE1124 and 16 more

Residues it binds most

LEU 4, GLY 4, MET 4, PHE 4, ALA 4, ILE 4, LYS 4, VAL 4, ASP 2, GLU 4 (residue and the binding sites it lines).

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