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Ligand · MS8

MS8 · (2R,3aR,7aR)-2-[(2S)-2-amino-3-hydroxy-3-oxo-propyl]-3,3a,5,6,7,7a-hexahydrofuro[4,5-b]pyran-2-carboxylic acid

MS8, (2R,3aR,7aR)-2-[(2S)-2-amino-3-hydroxy-3-oxo-propyl]-3,3a,5,6,7,7a-hexahydrofuro[4,5-b]pyran-2-carboxylic acid (C11 H17 N O6, 259.3 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site…

Component
MS8
Formula
C11 H17 N O6
Class
ligand
Structures
4
PDB entries
2

Binding sites

MS8 in 4 structures; the first of them:

  • 3FVG · Crystal structure of the human glutamate receptor, GluR5, ligand-binding core in complex… · MS8 A901 · binds GLU426, TYR474, PRO501, LEU502, THR503, ARG508, VAL670, GLY673 and 7 more
  • 3GBB · X-ray structure of iGluR5 ligand-binding core (S1S2) in complex with MSVIII-19 at 2.10A… · MS8 A258 · binds GLU13, TYR61, PRO88, LEU89, THR90, ARG95, VAL137, GLY140 and 7 more
  • 3FVG · Crystal structure of the human glutamate receptor, GLUR5, ligand- binding core in complex… · MS8 A901 · binds GLU426, TYR474, PRO501, LEU502, THR503, ARG508, VAL670, GLY673 and 7 more
  • 3GBB · X-ray structure of IGLUR5 ligand-binding core (S1S2) in complex with msviii-19 at 2.10A… · MS8 A258 · binds GLU13, TYR61, PRO88, LEU89, THR90, ARG95, VAL137, GLY140 and 7 more

Residues it binds most

SER 8, GLU 8, THR 8, TYR 8, ARG 8, GLY 8, LEU 8, PRO 8, VAL 8, MET 6 (residue and the binding sites it lines).

Found with

  • SO4 · Sulfate ion
  • GOL · Glycerol

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