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Ligand · MPW

MPW · 2-[2-(4-methoxypyridin-2-yl)ethyl]-3H-imidazo[4,5-b]pyridine

MPW, 2-[2-(4-methoxypyridin-2-yl)ethyl]-3H-imidazo[4,5-b]pyridine (C14 H14 N4 O, 254.3 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues it…

Component
MPW
Formula
C14 H14 N4 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

MPW in 2 structures; the first of them:

  • 3NW2 · Novel nanomolar Imidazopyridines as selective Nitric Oxide Synthase (iNOS) inhibitors… · MPW A1 · binds GLN257, ARG260, TYR341, PRO344, VAL346, PHE363, ASN364, GLY365 and 5 more
  • 3NW2 · Novel nanomolar imidazopyridines as selective nitric oxide synthase (inos) inhibitors… · MPW A1 · binds GLN257, ARG260, TYR341, PRO344, VAL346, PHE363, ASN364, GLY365 and 5 more

Residues it binds most

ARG 4, TYR 4, ASN 4, ASP 4, GLN 4, GLU 4, GLY 4, PHE 4, PRO 4, TRP 4 (residue and the binding sites it lines).

Found with

  • H4B · 5,6,7,8-tetrahydrobiopterin
  • HEM · Protoporphyrin IX containing Fe
  • SO4 · Sulfate ion

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