Ligand · ML8
ML8 · 8-cyclopentyl-6-[3-(hydroxymethyl)phenyl]-4-methyl-2-(methylamino)pyrido[2,3-d]pyrimidin-7(8H)-one
ML8, 8-cyclopentyl-6-[3-(hydroxymethyl)phenyl]-4-methyl-2-(methylamino)pyrido[2,3-d]pyrimidin-7(8H)-one (C21 H24 N4 O2, 364.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its…
- Component
- ML8
- Formula
- C21 H24 N4 O2
- Class
- ligand
- Structures
- 2
- PDB entries
- 1
Binding sites
ML8 in 2 structures; the first of them:
- 3ML8 · Discovery of the Highly Potent PI3K/mTOR Dual Inhibitor PF-04691502 through Structure… · ML8 A9999 · binds MET804, TRP812, ILE831, LYS833, ASP836, LEU838, ASP841, LEU845 and 12 more
- 3ML8 · Discovery of the highly potent PI3K/MTOR dual inhibitor pf-04691502 through structure… · ML8 A9999 · binds MET804, TRP812, ILE831, LYS833, ASP836, LEU838, ASP841, LEU845 and 12 more
Residues it binds most
ILE 2, ASP 2, LEU 2, MET 2, PHE 2, ALA 2, GLU 2, LYS 2, THR 2, TRP 2 (residue and the binding sites it lines).
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