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Ligand · MKT

MKT · 1,3,6,7-tetrahydroxy-2,8-bis(3-methylbut-2-en-1-yl)-9H-xanthen-9-one

MKT, 1,3,6,7-tetrahydroxy-2,8-bis(3-methylbut-2-en-1-yl)-9H-xanthen-9-one (C23 H24 O6, 396.4 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its residues within 4.5 Å, the residues…

Component
MKT
Formula
C23 H24 O6
Class
ligand
Structures
4
PDB entries
2

Binding sites

MKT in 4 structures; the first of them:

  • 4Y9E · Crystal structure of V30M mutated transthyretin in complex with gamma-mangostin · MKT A200 · binds LYS15, LEU17, THR106, ALA108, ALA109, LEU110, SER117, THR118 and 2 more
  • 4Y9F · Crystal structure of V30M mutated transthyretin with bromide in complex with… · MKT A201 · binds LYS15, LEU17, THR106, ALA108, ALA109, LEU110, SER117, THR118 and 2 more
  • 4Y9E · Crystal structure of V30M mutated transthyretin in complex with gamma- mangostin · MKT A200 · binds LYS15, LEU17, THR106, ALA108, ALA109, LEU110, SER117, THR118 and 2 more
  • 4Y9F · Crystal structure of V30M mutated transthyretin with bromide in complex with… · MKT A201 · binds LYS15, LEU17, THR106, ALA108, ALA109, LEU110, SER117, THR118 and 2 more

Residues it binds most

LEU 8, THR 8, ALA 8, SER 8, LYS 8, VAL 8, PRO 4 (residue and the binding sites it lines).

Found with

  • BR · Bromide ion
  • CL · Chloride ion

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