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Ligand · MIC

MIC · Alpha-methylisocitric acid

MIC, Alpha-methylisocitric acid (C7 H10 O7, 206.2 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (2 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found with…

Component
MIC
Formula
C7 H10 O7
Class
ligand
Structures
2
PDB entries
2

Binding sites

MIC in 2 structures; the first of them:

  • 1AMI · Steric and conformational features of the aconitase mechanism · MIC A755 · binds GLN72, ALA74, THR75, HIS101, ASP165, SER166, HIS167, ILE425 and 6 more
  • 7XP1 · Crystal structure of PmiR from Pseudomonas aeruginosa · MIC A302 · binds TYR92, ARG95, GLN140, GLY142, ASP143, TYR144, HIS147, ARG175 and 7 more

Residues it binds most

ARG 2, HIS 2, SER 2, ALA 2, ASP 2, GLN 2, THR 2, TYR 1, ASN 1, GLY 1 (residue and the binding sites it lines).

Found with

  • SF4 · Iron/sulfur cluster
  • ZN · Zinc ion
  • SO4 · Sulfate ion
  • GOL · Glycerol

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