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Ligand · MHR

MHR · 4-(4-propoxy-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-2-amine

MHR, 4-(4-propoxy-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-2-amine (C14 H15 N5 O, 269.3 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues it…

Component
MHR
Formula
C14 H15 N5 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

MHR in 2 structures; the first of them:

  • 3BHU · Structure of phosphorylated Thr160 CDK2/cyclin A in complex with the inhibitor meriolin 5 · MHR A299 · binds ILE10, TYR15, VAL18, ALA31, LYS33, GLU51, LEU55, VAL64 and 10 more
  • 3BHU · Structure of phosphorylated THR160 CDK2/CYCLIN a in complex with the inhibitor meriolin 5 · MHR A299 · binds ILE10, TYR15, VAL18, ALA31, LYS33, GLU51, LEU55, VAL64 and 10 more

Residues it binds most

LEU 4, PHE 4, ALA 4, GLU 4, VAL 4, ASN 4, ASP 4, GLN 4, ILE 4, LYS 4 (residue and the binding sites it lines).

Found with

  • MG · Magnesium ion

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