Ligand · MH4
MH4 · 1-methyl-8-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-N-[(2-methylpyridin-4-yl)methyl]-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide
MH4, 1-methyl-8-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-N-[(2-methylpyridin-4-yl)methyl]-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide (C29 H33 N9 O, 523.6 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1…
- Component
- MH4
- Formula
- C29 H33 N9 O
- Class
- ligand
- Structures
- 2
- PDB entries
- 1
Binding sites
MH4 in 2 structures; the first of them:
- 2XCK · Crystal structure of PDK1 in complex with a pyrazoloquinazoline inhibitor · MH4 A1360 · binds LEU88, GLY89, GLU90, GLY91, SER94, THR95, THR96, ALA109 and 12 more
- 2XCK · Crystal structure of PDK1 in complex with a pyrazoloquinazoline inhibitor · MH4 A1360 · binds LEU88, GLY89, GLU90, GLY91, SER94, THR95, THR96, ALA109 and 12 more
Residues it binds most
GLY 2, LEU 2, THR 2, ALA 2, GLU 2, LYS 2, SER 2, ASP 2, TYR 2, VAL 2 (residue and the binding sites it lines).
Found with
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