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Ligand · MB8

MB8 · (2Z)-2-methylbut-2-enoic acid

MB8, (2Z)-2-methylbut-2-enoic acid (C5 H8 O2, 100.1 g/mol), in the MolNFT structures on GenesisL1: bound in 10 records (5 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found…

Component
MB8
Formula
C5 H8 O2
Class
ligand
Structures
10
PDB entries
5

Binding sites

MB8 in 10 structures; the first of them:

  • 4MQ9 · Crystal structure of Thermus thermophilus RNA polymerase holoenzyme in complex with… · MB8 I101 · binds ARG409, PRO444, ASN448, 2RA1
  • 4OIN · Crystal structure of Thermus thermophilus transcription initiation complex soaked with… · MB8 I101 · binds PRO444, ASN448, 2RA1
  • 4OIP · Crystal structure of Thermus thermophilus transcription initiation complex soaked with… · MB8 I101 · binds PRO444, ASN448, 2RA1
  • 4OIQ · Crystal structure of Thermus thermophilus transcription initiation complex soaked with… · MB8 I101 · binds DC16, DG17, 2RA1, DSN2
  • 4OIR · Crystal structure of Thermus thermophilus RNA polymerase transcription initiation complex… · MB8 I101 · binds DG17, 2RA1, DSN2
  • 4MQ9 · Crystal structure of thermus thermophilus RNA polymerase holoenzyme in complex with… · MB8 I101 · binds ARG409, PRO444, ASN448, 2RA1
  • 4OIN · Crystal structure of thermus thermophilus transcription initiation complex soaked with… · MB8 I101 · binds PRO444, ASN448, 2RA1
  • 4OIP · Crystal structure of thermus thermophilus transcription initiation complex soaked with… · MB8 I101 · binds PRO444, ASN448, 2RA1
  • 4OIQ · Crystal structure of thermus thermophilus transcription initiation complex soaked with… · MB8 I101 · binds DC16, DG17, 2RA1, DSN2
  • 4OIR · Crystal structure of thermus thermophilus RNA polymerase transcription initiation complex… · MB8 I101 · binds DG17, 2RA1, DSN2

Residues it binds most

2RA 10, ASN 6, PRO 6, DG 4, DSN 4, ARG 2, DC 2 (residue and the binding sites it lines).

Found with

  • MG · Magnesium ion
  • ZN · Zinc ion
  • ATP · Adenosine-5'-triphosphate
  • RFV · rifamycin SV

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