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Ligand · LZR

LZR · 6-(cycloprop-2-en-1-ylmethoxy)-2-[6-(cyclopropylmethyl)-5-oxo-3,4,5,6-tetrahydro-2,6-naphthyridin-2(1H)-yl]-7-methoxyquinazolin-4(3H)-one

LZR, 6-(cycloprop-2-en-1-ylmethoxy)-2-[6-(cyclopropylmethyl)-5-oxo-3,4,5,6-tetrahydro-2,6-naphthyridin-2(1H)-yl]-7-methoxyquinazolin-4(3H)-one (C25 H26 N4 O4, 446.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB…

Component
LZR
Formula
C25 H26 N4 O4
Class
ligand
Structures
2
PDB entries
1

Binding sites

LZR in 2 structures; the first of them:

  • 2W0V · Crystal structure of Glmu from Haemophilus influenzae in complex with quinazoline… · LZR A1454 · binds LEU11, ALA12, ALA13, GLY14, LYS25, VAL26, GLN76, GLN79 and 16 more
  • 2W0V · Crystal structure of glmu from haemophilus influenzae in complex with quinazoline… · LZR A1454 · binds LEU11, ALA12, ALA13, GLY14, LYS25, VAL26, GLN76, GLN79 and 16 more

Residues it binds most

ALA 2, GLY 2, VAL 2, GLN 2, LEU 2, THR 2, TYR 2, ASN 2, ASP 2, GLU 2 (residue and the binding sites it lines).

Found with

  • SO4 · Sulfate ion
  • PG4 · Tetraethylene glycol
  • PGE · Triethylene glycol

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