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Ligand · LZK

LZK · 6-(2,6-dimethoxyphenyl)pyrido[2,3-d]pyrimidine-2,7-diamine

LZK, 6-(2,6-dimethoxyphenyl)pyrido[2,3-d]pyrimidine-2,7-diamine (C15 H15 N5 O2, 297.3 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues it binds…

Component
LZK
Formula
C15 H15 N5 O2
Class
ligand
Structures
2
PDB entries
1

Binding sites

LZK in 2 structures; the first of them:

  • 2V59 · Crystal structure of biotin carboxylase from E.COLI in complex with potent inhibitor 2 · LZK A1446 · binds VAL131, ILE157, LYS159, GLY165, MET169, GLU201, LYS202, TYR203 and 8 more
  • 2V59 · Crystal structure of biotin carboxylase from E.COLI in complex with potent inhibitor 2 · LZK A1446 · binds VAL131, ILE157, LYS159, GLY165, MET169, GLU201, LYS202, TYR203 and 8 more

Residues it binds most

ILE 4, HIS 4, LEU 4, LYS 4, GLN 4, GLU 4, MET 4, TYR 4, VAL 4, GLY 2 (residue and the binding sites it lines).

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