Ligand · LZI

LZI · (4R)-4-{[(5-chlorothiophen-2-yl)carbonyl]amino}-N-(cyclopropylmethyl)-1-(2-{[2-fluoro-4-(2-oxopyridin-1(2H)-yl)phenyl]amino}-2-oxoethyl)-L-prolinamide

LZI, (4R)-4-{[(5-chlorothiophen-2-yl)carbonyl]amino}-N-(cyclopropylmethyl)-1-(2-{[2-fluoro-4-(2-oxopyridin-1(2H)-yl)phenyl]amino}-2-oxoethyl)-L-prolinamide (C27 H27 Cl F N5 O4 S, 572.0 g/mol), in the MolNFT structures on GenesisL1: bound…

Component: LZI
Formula: C27 H27 Cl F N5 O4 S
Class: ligand
Structures: 2
PDB entries: 1

Binding sites

LZI in 2 structures; the first of them:

2VWM · Aminopyrrolidine Factor Xa inhibitor · LZI A1244 · binds LYS96, GLU97, THR98, TYR99, ARG143, GLU147, LYS148, PHE174 and 16 more
2VWM · Aminopyrrolidine factor xa inhibitor · LZI A1244 · binds LYS96, GLU97, THR98, TYR99, ARG143, GLU147, LYS148, PHE174 and 16 more

Residues it binds most

GLU 4, GLY 4, CYS 4, SER 4, TYR 4, ILE 4, LYS 4, ALA 4, ARG 4, ASP 4 (residue and the binding sites it lines).

Found with

NA · Sodium ion

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