GL1X · GenesisL1 explorer

Ligand · LX2

LX2 · [4-(3-{[2-chloro-3-(trifluoromethyl)benzyl](2,2-diphenylethyl)amino}propoxy)-1H-indol-1-yl]acetic acid

LX2, [4-(3-{[2-chloro-3-(trifluoromethyl)benzyl](2,2-diphenylethyl)amino}propoxy)-1H-indol-1-yl]acetic acid (C35 H32 Cl F3 N2 O3, 621.1 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site…

Component
LX2
Formula
C35 H32 Cl F3 N2 O3
Class
ligand
Structures
2
PDB entries
1

Binding sites

LX2 in 2 structures; the first of them:

  • 3FC6 · hRXRalpha & mLXRalpha with an indole Pharmacophore, SB786875 · LX2 B1 · binds ASN223, PHE252, PHE255, THR256, LEU258, ALA259, VAL261, SER262 and 22 more
  • 3FC6 · Hrxralpha & mlxralpha with an indole pharmacophore, SB786875 · LX2 B1 · binds ASN223, PHE252, PHE255, THR256, LEU258, ALA259, VAL261, SER262 and 22 more

Residues it binds most

LEU 4, PHE 4, ILE 4, THR 4, GLU 4, VAL 4, ALA 4, ARG 4, ASN 4, GLN 4 (residue and the binding sites it lines).

Found with

  • REA · Retinoic acid

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.