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Ligand · LUW

LUW · 4-oxidanyl-~{N}-[(4-phenoxyphenyl)methyl]-2-pyrazol-1-yl-pyrimidine-5-carboxamide

LUW, 4-oxidanyl-~{N}-[(4-phenoxyphenyl)methyl]-2-pyrazol-1-yl-pyrimidine-5-carboxamide (C21 H17 N5 O3, 387.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5…

Component
LUW
Formula
C21 H17 N5 O3
Class
ligand
Structures
2
PDB entries
1

Binding sites

LUW in 2 structures; the first of them:

  • 6ST3 · HIF prolyl hydroxylase 2 (PHD2/ EGLN1) in complex with… · LUW A601 · binds ARG252, TRP258, THR296, MET299, TYR303, TYR310, HIS313, ASP315 and 8 more
  • 6ST3 · Hif prolyl hydroxylase 2 (PHD2/ EGLN1) in complex with 4-hydroxy-N-(4… · LUW A601 · binds ARG252, TRP258, THR296, MET299, TYR303, TYR310, HIS313, ASP315 and 6 more

Residues it binds most

ARG 4, ASP 4, HIS 4, TRP 4, TYR 4, MET 4, PHE 4, THR 4, VAL 4, LEU 2 (residue and the binding sites it lines).

Found with

  • MN · Manganese (II) ion
  • FMT · Formic acid

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