GL1X · GenesisL1 explorer

Ligand · LRT

LRT · 5-(1,4-diazepan-1-ylsulfonyl)isoquinolin-1-amine

LRT, 5-(1,4-diazepan-1-ylsulfonyl)isoquinolin-1-amine (C14 H18 N4 O2 S, 306.4 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (3 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most…

Component
LRT
Formula
C14 H18 N4 O2 S
Class
ligand
Structures
4
PDB entries
3

Binding sites

LRT in 4 structures; the first of them:

  • 6SQ1 · Crystal structure of cAMP-dependent Protein Kinase A (CHO PKA) in complex with… · LRT A403 · binds LEU49, GLY50, VAL57, ALA70, VAL104, MET120, GLU121, TYR122 and 7 more
  • 6SQ1 · Crystal structure of camp-dependent protein kinase a (cho PKA) in complex with… · LRT A403 · binds LEU49, GLY50, VAL57, ALA70, VAL104, MET120, GLU121, TYR122 and 7 more
  • 6Y2U · Crystal structure of the camp-dependent protein kinase a cocrystallized with aminofasudil… · LRT A401 · binds LEU49, GLY50, VAL57, ALA70, VAL104, MET120, GLU121, TYR122 and 8 more
  • 6YNT · Crystal structure of the camp-dependent protein kinase a in complex with aminofasudil and… · LRT A405 · binds LEU49, GLY50, THR51, VAL57, ALA70, VAL104, MET120, GLU121 and 8 more

Residues it binds most

GLU 4, VAL 4, LEU 4, THR 4, ALA 4, ASN 4, GLY 4, MET 4, PHE 4, TYR 4 (residue and the binding sites it lines).

Found with

  • DMS · Dimethyl sulfoxide
  • MPD · (4S)-2-methyl-2,4-pentanediol
  • MRD · (4R)-2-methylpentane-2,4-diol

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.