Ligand · LQ5

LQ5 · 1-[4-(2-azanylpyrimidin-4-yl)oxyphenyl]-3-[4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]urea

LQ5, 1-[4-(2-azanylpyrimidin-4-yl)oxyphenyl]-3-[4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]urea (C24 H26 F3 N7 O2, 501.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site…

Component: LQ5
Formula: C24 H26 F3 N7 O2
Class: ligand
Structures: 2
PDB entries: 1

Binding sites

LQ5 in 2 structures; the first of them:

5A14 · Human CDK2 with type II inhibitor · LQ5 A1297 · binds ILE10, VAL18, ALA31, LYS33, GLU51, LEU54, LEU55, LEU58 and 16 more
5A14 · Human CDK2 with type II inhibitor · LQ5 A1297 · binds ILE10, VAL18, ALA31, LYS33, GLU51, LEU54, LEU55, LEU58 and 16 more

Residues it binds most

LEU 2, PHE 4, ILE 4, LYS 4, VAL 2, ALA 2, GLU 2, ARG 2, ASP 2, HIS 2 (residue and the binding sites it lines).

Found with

ACE · Acetyl group

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