Ligand · LMM

LMM · N2-[(1S)-1-(5-fluoropyrimidin-2-yl)ethyl]-7-methyl-N4-(1-methylimidazol-4-yl)thieno[3,2-d]pyrimidine-2,4-diamine

LMM, N2-[(1S)-1-(5-fluoropyrimidin-2-yl)ethyl]-7-methyl-N4-(1-methylimidazol-4-yl)thieno[3,2-d]pyrimidine-2,4-diamine (C17 H17 F N8 S, 384.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding…

Component: LMM
Formula: C17 H17 F N8 S
Class: ligand
Structures: 2
PDB entries: 1

Binding sites

LMM in 2 structures; the first of them:

4C61 · Inhibitors of Jak2 Kinase domain · LMM A2133 · binds LEU855, GLY856, VAL863, ALA880, VAL911, MET929, GLU930, TYR931 and 11 more
4C61 · Inhibitors of JAK2 kinase domain · LMM A2133 · binds LEU855, GLY856, VAL863, ALA880, VAL911, MET929, GLU930, TYR931 and 11 more

Residues it binds most

GLY 4, LEU 4, TYR 4, VAL 4, ALA 4, ARG 4, ASN 4, ASP 4, GLU 4, ILE 4 (residue and the binding sites it lines).

Found with

ACT · Acetate ion

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