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Ligand · LIZ

LIZ · N-{(1S,2S)-2-[bis(carboxymethyl)amino]cyclohexyl}-N-{(2R)-2-[bis(carboxymethyl)amino]-3-[4-({[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]carbamothioyl}amino)phenyl]propyl}glycine

LIZ, N-{(1S,2S)-2-[bis(carboxymethyl)amino]cyclohexyl}-N-{(2R)-2-[bis(carboxymethyl)amino]-3-[4-({[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]carbamothioyl}amino)phenyl]propyl}glycine (C30 H45 N5 O13 S, 715.8 g/mol), in the MolNFT structures on…

Component
LIZ
Formula
C30 H45 N5 O13 S
Class
ligand
Structures
6
PDB entries
3

Binding sites

LIZ in 6 structures; the first of them:

  • 3DSZ · Engineered human lipocalin 2 in complex with Y-DTPA · LIZ A187 · binds GLN33, ARG36, THR52, GLN54, VAL66, ALA68, ARG70, ASP77 and 7 more
  • 4IAW · Engineered human lipocalin 2 (C26) in complex with Y-DTPA · LIZ A201 · binds GLN33, ARG36, THR52, GLN54, VAL66, ALA68, ARG70, GLU77 and 7 more
  • 4IAX · Engineered human lipocalin 2 (CL31) in complex with Y-DTPA · LIZ A201 · binds GLN33, ARG36, THR52, GLN54, VAL66, ALA68, ARG70, ARG72 and 8 more
  • 3DSZ · Engineered human lipocalin 2 in complex with Y-dtpa · LIZ A187 · binds GLN33, ARG36, THR52, GLN54, VAL66, ALA68, ARG70, ASP77 and 7 more
  • 4IAW · Engineered human lipocalin 2 (C26) in complex with Y-dtpa · LIZ A201 · binds GLN33, ARG36, THR52, GLN54, VAL66, ALA68, ARG70, GLU77 and 7 more
  • 4IAX · Engineered human lipocalin 2 (CL31) in complex with Y-dtpa · LIZ A201 · binds GLN33, ARG36, THR52, GLN54, VAL66, ALA68, ARG70, ARG72 and 8 more

Residues it binds most

ARG 12, GLN 12, PHE 12, TYR 12, THR 12, ALA 12, LEU 12, MET 12, VAL 12, GLU 8 (residue and the binding sites it lines).

Found with

  • YT3 · Yttrium (III) ion

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