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Ligand · LHD

LHD · 2-[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]ethyl-[[4-azanyl-1-(methoxymethyl)-2-oxidanylidene-pyrimidin-5-yl]methyl]azanium

LHD, 2-[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]ethyl-[[4-azanyl-1-(methoxymethyl)-2-oxidanylidene-pyrimidin-5-yl]methyl]azanium (C18 H26 N9 O5 +1, 448.5 g/mol), in the MolNFT structures on GenesisL1…

Component
LHD
Formula
C18 H26 N9 O5 +1
Class
ligand
Structures
1
PDB entries
1

Binding sites

LHD in 1 structure; the first of them:

  • 5TBJ · Crystal structure of mouse CARM1 in complex with inhibitor LH1452 · LHD A501 · binds TYR150, PHE151, TYR154, GLN159, MET163, GLY193, GLU215, ALA216 and 12 more

Residues it binds most

GLU 4, MET 4, TYR 4, GLY 4, PHE 4, SER 4, ALA 4, GLN 4, LYS 4, TRP 4 (residue and the binding sites it lines).

Found with

  • DXE · 1,2-dimethoxyethane
  • EDO · 1,2-ethanediol
  • PEG · Di(hydroxyethyl)ether
  • PG6 · 1-(2-methoxy-ethoxy)-2-{2-[2-(2-methoxy-ethoxy]-ethoxy}-ethane

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