LGN · N-[(2S,3R,4E)-1-{[alpha-D-galactopyranosyl-(1->3)-beta-D-galactopyranosyl-(1->4)-beta-D-glucopyranosyl]oxy}-3-hydroxyoctadec-4-en-2-yl]hexacosanamide

Binding sites

LGN in 4 structures; the first of them:

• 3RZC · Structure of the self-antigen iGb3 bound to mouse CD1d and in complex with the iNKT TCR · LGN A286 · binds PHE10, CYS12, GLN14, SER28, VAL30, HIS38, TRP40, ILE47 and 41 more
• 3SCM · Crystal structure of autoreactive-Valpha14-Vbeta6 NKT TCR in complex with… · LGN A307 · binds PHE10, CYS12, GLN14, SER28, VAL30, ILE47, TRP63, LEU66 and 38 more
• 3RZC · Structure of the self-antigen IGB3 bound to mouse CD1D and in complex with the inkt TCR · LGN A286 · binds PHE10, CYS12, GLN14, SER28, VAL30, HIS38, TRP40, ILE47 and 41 more
• 3SCM · Crystal structure of autoreactive-VALPHA14-VBETA6 nkt TCR in complex with… · LGN A307 · binds PHE10, CYS12, GLN14, SER28, VAL30, ILE47, TRP63, LEU66 and 38 more

Residues it binds most

LEU 4, VAL 4, PHE 4, ASP 4, TRP 4, ILE 4, THR 4, ALA 4, CYS 4, GLY 4 (residue and the binding sites it lines).

Found with

• NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose
• FUL · beta-L-fucopyranose
• MAN · alpha-D-mannopyranose