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Ligand · LG8

LG8 · 3-(8-dimethylaminomethyl-6,7,8,9-tetrahydro-pyrido[1,2-a]indol-10-yl)-4-(1-methyl-1H-indol-3-yl)-pyrrole-2,5-dione

LG8, 3-(8-dimethylaminomethyl-6,7,8,9-tetrahydro-pyrido[1,2-a]indol-10-yl)-4-(1-methyl-1H-indol-3-yl)-pyrrole-2,5-dione (C28 H28 N4 O2 +2, 452.6 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding…

Component
LG8
Formula
C28 H28 N4 O2 +2
Class
ligand
Structures
2
PDB entries
1

Binding sites

LG8 in 2 structures; the first of them:

  • 2JED · The crystal structure of the kinase domain of the protein kinase C theta in complex with… · LG8 A1701 · binds LEU386, GLY387, PHE391, VAL394, ALA407, LYS409, GLU428, THR442 and 11 more
  • 2JED · The crystal structure of the kinase domain of the protein kinase C theta in complex with… · LG8 A1701 · binds LEU386, GLY387, PHE391, VAL394, ALA407, LYS409, GLU428, THR442 and 11 more

Residues it binds most

ASP 4, LEU 4, ALA 4, GLU 4, PHE 4, ASN 4, GLY 4, LYS 4, MET 4, THR 4 (residue and the binding sites it lines).

Found with

  • MPD · (4S)-2-methyl-2,4-pentanediol

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