GL1X · GenesisL1 explorer

Ligand · LF2

LF2 · (2S)-[6-bromo-4-(4-chlorophenyl)-2-methylquinolin-3-yl](tert-butoxy)ethanoic acid

LF2, (2S)-[6-bromo-4-(4-chlorophenyl)-2-methylquinolin-3-yl](tert-butoxy)ethanoic acid (C22 H21 Br Cl N O3, 462.8 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its residues…

Component
LF2
Formula
C22 H21 Br Cl N O3
Class
ligand
Structures
4
PDB entries
2

Binding sites

LF2 in 4 structures; the first of them:

  • 4GVM · HIV-1 Integrase Catalytic Core Domain A128T Mutant Complexed with Allosteric Inhibitor · LF2 A303 · binds GLN95, ALA98, TYR99, LEU102, THR124, THR125, THR128, ALA129 and 1 more
  • 4GW6 · HIV-1 Integrase Catalytic Core Domain Complexed with Allosteric Inhibitor · LF2 A303 · binds GLN95, ALA98, TYR99, LEU102, THR125, ALA128, ALA129, TRP132
  • 4GVM · HIV-1 integrase catalytic core domain A128T mutant complexed with allosteric inhibitor · LF2 A303 · binds GLN95, ALA98, TYR99, LEU102, THR124, THR125, THR128, ALA129 and 1 more
  • 4GW6 · HIV-1 integrase catalytic core domain complexed with allosteric inhibitor · LF2 A303 · binds GLN95, ALA98, TYR99, LEU102, THR125, ALA128, ALA129, TRP132

Residues it binds most

ALA 4, THR 4, GLN 4, LEU 4, TRP 4, TYR 4 (residue and the binding sites it lines).

Found with

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.