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Ligand · LCS

LCS · [5-hydroxy-6-methyl-4-({[(4E)-3-oxo-1,2-oxazolidin-4-ylidene]amino}methyl)pyridin-3-yl]methyl dihydrogen phosphate

LCS, [5-hydroxy-6-methyl-4-({[(4E)-3-oxo-1,2-oxazolidin-4-ylidene]amino}methyl)pyridin-3-yl]methyl dihydrogen phosphate (C11 H14 N3 O7 P, 331.2 g/mol), in the MolNFT structures on GenesisL1: bound in 3 records (3 PDB entries). Every…

Component
LCS
Formula
C11 H14 N3 O7 P
Class
ligand
Structures
3
PDB entries
3

Binding sites

LCS in 3 structures; the first of them:

  • 6QP1 · Crystal structure of the PLP-bound C-S lyase in the external aldimine form from… · LCS A501 · binds VAL46, ALA47, GLY106, ILE107, VAL108, TYR132, PHE135, ALA180 and 11 more
  • 8AHU · Crystal structure of D-amino acid aminotrensferase from Haliscomenobacter hydrossis… · LCS A302 · binds PHE33, TYR35, TYR49, ARG52, ARG137, LYS143, TYR147, GLU176 and 13 more
  • 8AIE · Crystal structure of D-amino acid aminotransferase from Aminobacterium colombiense… · LCS A301 · binds THR34, HIS48, ARG51, ARG136, LYS142, TYR146, GLU172, GLY173 and 14 more

Residues it binds most

ARG 4, SER 4, THR 2, TYR 4, ALA 3, GLY 4, ILE 3, LYS 4, VAL 3, GLU 4 (residue and the binding sites it lines).

Found with

  • M7L · 3-azanyloxy-2-[(~{E})-[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methylideneamino]propanoic acid
  • PMP · 4'-deoxy-4'-aminopyridoxal-5'-phosphate
  • GOL · Glycerol

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