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Ligand · LC8

LC8 · 4-(furan-2-ylmethylamino)-3-nitro-benzenesulfonamide

LC8, 4-(furan-2-ylmethylamino)-3-nitro-benzenesulfonamide (C11 H11 N3 O5 S, 297.3 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues it binds…

Component
LC8
Formula
C11 H11 N3 O5 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

LC8 in 2 structures; the first of them:

  • 6SG6 · Human Carbonic Anhydrase II in complex with furan-containing benzenesulfonamide · LC8 A304 · binds GLN92, HIS94, HIS96, GLU106, HIS119, VAL121, PHE131, VAL143 and 8 more
  • 6SG6 · Human carbonic anhydrase II in complex with furan-containing benzenesulfonamide · LC8 A304 · binds GLN92, HIS94, HIS96, HIS119, VAL121, PHE131, LEU198, THR199 and 4 more

Residues it binds most

HIS 2, PRO 2, THR 2, LEU 2, VAL 2, GLN 2, PHE 2, TRP 2, GLU 1, SER 1 (residue and the binding sites it lines).

Found with

  • BE7 · (4-carboxyphenyl)(chloro)mercury
  • NA · Sodium ion
  • ZN · Zinc ion
  • DMS · Dimethyl sulfoxide

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