GL1X · GenesisL1 explorer

Ligand · LB7

LB7 · 6-[(cyclopropanecarbonyl)amino]-4-{[2-methoxy-3-(1-methyl-1H-1,2,4-triazol-3-yl)phenyl]amino}-N-methylpyridazine-3-carboxamide

LB7, 6-[(cyclopropanecarbonyl)amino]-4-{[2-methoxy-3-(1-methyl-1H-1,2,4-triazol-3-yl)phenyl]amino}-N-methylpyridazine-3-carboxamide (C20 H22 N8 O3, 422.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry).…

Component
LB7
Formula
C20 H22 N8 O3
Class
ligand
Structures
2
PDB entries
1

Binding sites

LB7 in 2 structures; the first of them:

  • 6NZP · Crystal structure of tyrosine kinase 2 JH2 (pseudo kinase domain) complexed with… · LB7 A901 · binds LEU595, GLN597, GLY598, VAL603, VAL640, LYS642, ALA671, THR687 and 11 more
  • 6NZP · Crystal structure of tyrosine kinase 2 JH2 (pseudo kinase domain) complexed with… · LB7 A901 · binds LEU595, GLN597, GLY598, VAL603, VAL640, LYS642, ALA671, THR687 and 11 more

Residues it binds most

VAL 4, GLU 4, GLY 4, LEU 4, ALA 4, ARG 4, ASN 4, GLN 4, HIS 4, LYS 4 (residue and the binding sites it lines).

Found with

  • CL · Chloride ion

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.