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Ligand · LAS

LAS · N-acetyl-S-({(2R,3S,4R)-3-hydroxy-2-[(1S)-1-hydroxy-2-methylpropyl]-4-methyl-5-oxopyrrolidin-2-yl}carbonyl)cysteine

LAS, N-acetyl-S-({(2R,3S,4R)-3-hydroxy-2-[(1S)-1-hydroxy-2-methylpropyl]-4-methyl-5-oxopyrrolidin-2-yl}carbonyl)cysteine (C15 H24 N2 O7 S, 376.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding…

Component
LAS
Formula
C15 H24 N2 O7 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

LAS in 2 structures; the first of them:

  • 3DPM · Structure of mature CPAF complexed with lactacystin · LAS A800 · binds HIS105, PRO374, GLY375, GLY376, VAL378, SER499, CYS500, PHE503 and 3 more
  • 3DPM · Structure of mature cpaf complexed with lactacystin · LAS A800 · binds HIS105, PRO374, GLY375, GLY376, VAL378, SER499, CYS500, PHE503 and 3 more

Residues it binds most

GLY 4, PHE 4, VAL 4, CYS 4, HIS 4, PRO 4, SER 4, LEU 2 (residue and the binding sites it lines).

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