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Ligand · L63

L63 · N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]biphenyl-4-carboxamide

L63, N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]biphenyl-4-carboxamide (C17 H18 N2 O4, 314.3 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the…

Component
L63
Formula
C17 H18 N2 O4
Class
ligand
Structures
2
PDB entries
1

Binding sites

L63 in 2 structures; the first of them:

  • 4FW7 · Crystal Structure of the LpxC in complex with N-[(2S,3R)-3-HYDROXY-1-(HYDROXYAMINO)-1-OXOB… · L63 A302 · binds LEU18, MET62, GLU77, HIS78, THR190, PHE191, GLY192, ILE197 and 11 more
  • 4FW7 · Crystal structure of the lpxc in complex with N-[(2S,3R)-3-hydroxy-1… · L63 A302 · binds LEU18, MET62, GLU77, HIS78, THR190, PHE191, GLY192, ILE197 and 11 more

Residues it binds most

HIS 8, ALA 8, GLY 8, LEU 8, MET 8, PHE 8, SER 8, ASP 8, GLU 8, LYS 8 (residue and the binding sites it lines).

Found with

  • ZN · Zinc ion
  • ACT · Acetate ion
  • GOL · Glycerol

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