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Ligand · L59

L59 · N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]-4-(phenylethynyl)benzamide

L59, N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]-4-(phenylethynyl)benzamide (C19 H18 N2 O4, 338.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5…

Component
L59
Formula
C19 H18 N2 O4
Class
ligand
Structures
2
PDB entries
1

Binding sites

L59 in 2 structures; the first of them:

  • 4FW6 · Crystal Structure of the LpxC in complex with N-[(2S,3R)-3-HYDROXY-1-(HYDROXYAMINO)-1-OXOB… · L59 A302 · binds LEU18, HIS19, MET62, GLU77, HIS78, THR190, PHE191, GLY192 and 13 more
  • 4FW6 · Crystal structure of the lpxc in complex with N-[(2S,3R)-3-hydroxy-1… · L59 A302 · binds LEU18, HIS19, MET62, GLU77, HIS78, THR190, PHE191, GLY192 and 13 more

Residues it binds most

HIS 8, ALA 8, GLY 8, LEU 8, VAL 8, ARG 8, ASP 8, GLU 8, ILE 8, LYS 8 (residue and the binding sites it lines).

Found with

  • NA · Sodium ion
  • ZN · Zinc ion
  • ACT · Acetate ion
  • GOL · Glycerol
  • PEG · Di(hydroxyethyl)ether

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