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Ligand · L4V

L4V · 13-Chloro-14,16-dihydroxy-2-methyl-2,3,4,5,9,10-hexahydrobenz[c][1]azacyclotetradecine-1,11(8H,12H)-dione

L4V, 13-Chloro-14,16-dihydroxy-2-methyl-2,3,4,5,9,10-hexahydrobenz[c][1]azacyclotetradecine-1,11(8H,12H)-dione (C18 H22 Cl N O4, 351.8 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with…

Component
L4V
Formula
C18 H22 Cl N O4
Class
ligand
Structures
2
PDB entries
1

Binding sites

L4V in 2 structures; the first of them:

  • 4CE3 · Hsp90 N-terminal domain bound to macrolactam analogues of radicicol. · L4V A1215 · binds LEU34, ASN37, ALA38, ALA41, LYS44, ASP79, ILE82, GLY83 and 6 more
  • 4CE3 · HSP90 N-terminal domain bound to macrolactam analogues of radicicol. · L4V A1215 · binds LEU34, ASN37, ALA38, ALA41, LYS44, ASP79, ILE82, GLY83 and 6 more

Residues it binds most

LEU 2, ALA 2, ASN 2, ASP 2, GLY 2, ILE 2, LYS 2, MET 2, PHE 2, THR 2 (residue and the binding sites it lines).

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