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Ligand · L24

L24 · [[[2-amino-5,6,7,8-tetrahydro-4-hydroxy-pyrido[2,3-d]pyrimidin-6-yl]-ethyl]-phenyl]-carbonyl-glutamic acid

L24, [[[2-amino-5,6,7,8-tetrahydro-4-hydroxy-pyrido[2,3-d]pyrimidin-6-yl]-ethyl]-phenyl]-carbonyl-glutamic acid (C21 H25 N5 O6, 443.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with…

Component
L24
Formula
C21 H25 N5 O6
Class
ligand
Structures
2
PDB entries
1

Binding sites

L24 in 2 structures; the first of them:

  • 1DIA · Human methylenetetrahydrofolate dehydrogenase / cyclohydrolase complexed with NADP and… · L24 A3001 · binds TYR52, VAL55, LYS56, GLN100, LEU101, PRO102, PRO272, GLY273 and 4 more
  • 1DIA · Human methylenetetrahydrofolate dehydrogenase / cyclohydrolase complexed with NADP and… · L24 A3001 · binds TYR52, VAL55, LYS56, GLN100, LEU101, PRO102, PRO272, GLY273 and 4 more

Residues it binds most

PRO 2, GLY 2, VAL 2, GLN 2, LEU 2, LYS 2, THR 2, TYR 2 (residue and the binding sites it lines).

Found with

  • NAP · Nadp nicotinamide-adenine-dinucleotide phosphate

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