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Ligand · L0Q

L0Q · ~{N}-[3-[6-[4-(4-methylpiperazin-1-yl)phenyl]-4-propan-2-yloxy-7~{H}-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]propanamide

L0Q, ~{N}-[3-[6-[4-(4-methylpiperazin-1-yl)phenyl]-4-propan-2-yloxy-7~{H}-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]propanamide (C29 H34 N6 O2, 498.6 g/mol), in the MolNFT structures on GenesisL1: bound in 1 record (1 PDB entry). Every binding…

Component
L0Q
Formula
C29 H34 N6 O2
Class
ligand
Structures
1
PDB entries
1

Binding sites

L0Q in 1 structure; the first of them:

  • 6S89 · Crystal structure of EGFR-T790M/C797S in complex with covalent pyrrolopyrimidine 19G · L0Q A1101 · binds LEU718, GLY719, VAL726, ALA743, MET790, GLN791, LEU792, MET793 and 3 more

Residues it binds most

LEU 1, GLY 1, MET 1, ALA 1, GLN 1, PRO 1, VAL 1 (residue and the binding sites it lines).

Found with

  • MES · 2-(N-morpholino)-ethanesulfonic acid

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