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Ligand · KZZ

KZZ · 1-(2-azanylethyl)-5-[(4-methoxynaphthalen-1-yl)methyl]-~{N}-(naphthalen-1-ylmethyl)-6,7-dihydro-4~{H}-pyrazolo[4,3-c]pyridine-3-carboxamide

KZZ, 1-(2-azanylethyl)-5-[(4-methoxynaphthalen-1-yl)methyl]-~{N}-(naphthalen-1-ylmethyl)-6,7-dihydro-4~{H}-pyrazolo[4,3-c]pyridine-3-carboxamide (C32 H33 N5 O2, 519.6 g/mol), in the MolNFT structures on GenesisL1: bound in 1 record (1 PDB…

Component
KZZ
Formula
C32 H33 N5 O2
Class
ligand
Structures
1
PDB entries
1

Binding sites

KZZ in 1 structure; the first of them:

  • 5N8V · Targeting the PEX14-PEX5 interaction by small molecules provides novel therapeutic routes… · KZZ A101 · binds ASN13, ALA14, GLU16, PHE17, ARG22, VAL23, THR26, SER30 and 4 more

Residues it binds most

PHE 4, LEU 4, ALA 4, ARG 4, ASN 4, GLU 4, LYS 4, SER 4, THR 4, VAL 4 (residue and the binding sites it lines).

Found with

  • CL · Chloride ion
  • SO4 · Sulfate ion
  • BME · Beta-mercaptoethanol

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