Ligand · KZL
KZL · 5-[(2-amino-1,1-dimethylethyl)amino]-7-[(3,5-dimethoxyphenyl)amino][1,2,4]triazolo[4,3-c]pyrimidine-8-carboxamide
KZL, 5-[(2-amino-1,1-dimethylethyl)amino]-7-[(3,5-dimethoxyphenyl)amino][1,2,4]triazolo[4,3-c]pyrimidine-8-carboxamide (C18 H24 N8 O3, 400.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding…
- Component
- KZL
- Formula
- C18 H24 N8 O3
- Class
- ligand
- Structures
- 2
- PDB entries
- 1
Binding sites
KZL in 2 structures; the first of them:
- 3AC4 · Crystal structure of triazolo pyrimidine derivative bound to the kinase domain of human… · KZL A513 · binds LEU251, GLY252, VAL259, ALA271, GLU317, TYR318, MET319, GLU320 and 3 more
- 3AC4 · Crystal structure of triazolo pyrimidine derivative bound to the kinase domain of human… · KZL A513 · binds LEU251, GLY252, VAL259, ALA271, GLU317, TYR318, MET319, GLU320 and 3 more
Residues it binds most
GLU 2, GLY 2, LEU 2, ALA 2, MET 2, SER 2, TYR 2, VAL 2 (residue and the binding sites it lines).
Found with
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