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Ligand · KZD

KZD · (2S)-tert-butoxy[(4S)-7-(4,4-dimethylpiperidin-1-yl)-8-{4-[2-(4-fluorophenyl)ethoxy]phenyl}-2,5-dimethylimidazo[1,2-a]pyridin-6-yl]acetic acid

KZD, (2S)-tert-butoxy[(4S)-7-(4,4-dimethylpiperidin-1-yl)-8-{4-[2-(4-fluorophenyl)ethoxy]phenyl}-2,5-dimethylimidazo[1,2-a]pyridin-6-yl]acetic acid (C36 H44 F N3 O4, 601.8 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records…

Component
KZD
Formula
C36 H44 F N3 O4
Class
ligand
Structures
2
PDB entries
1

Binding sites

KZD in 2 structures; the first of them:

  • 7U2U · CRYSTAL STRUCTURE OF HIV-1 INTEGRASE COMPLEXED WITH Compound-2a AKA… · KZD A301 · binds GLN95, ALA98, TYR99, LEU102, THR124, THR125, LYS127, ALA128 and 3 more
  • 7U2U · Crystal structure of HIV-1 integrase complexed with compound-2A aka… · KZD A301 · binds GLN95, THR124, THR125, LYS127, ALA128, ALA129, TRP131, TRP132

Residues it binds most

ALA 2, THR 2, TRP 2, GLN 2, LYS 2, LEU 1, TYR 1 (residue and the binding sites it lines).

Found with

  • SO4 · Sulfate ion

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