GL1X · GenesisL1 explorer

Ligand · KZA

KZA · 9-[(1~{R},3~{R},6~{R},8~{R},9~{R},10~{R},12~{R},15~{R},17~{R},18~{S})-8-(6-aminopurin-9-yl)-9,18-bis(fluoranyl)-3,12-bis(oxidanylidene)-3,12-bis(sulfanyl)-2,4,7,11,13-pentaoxa-3$l^{5},12$l^{5}-diphosphatricyclo[13.3.0.0^{6,10}]octadecan-17-yl]purin-6-amine

KZA, 9-[(1~{R},3~{R},6~{R},8~{R},9~{R},10~{R},12~{R},15~{R},17~{R},18~{S})-8-(6-aminopurin-9-yl)-9,18-bis(fluoranyl)-3,12-bis(oxidanylidene)-3,12-bis(sulfanyl)-2,4,7,11,13-pentaoxa-3$l^{5},12$l^{5}-diphosphatricyclo[13.3.0.0^{6,10}]octadeca…

Component
KZA
Formula
C21 H24 F2 N10 O7 P2 S2
Class
ligand
Structures
1
PDB entries
1

Binding sites

KZA in 1 structure; the first of them:

  • 8A2X · Crystal structure of human STING in complex with… · KZA A401 · binds SER162, TYR163, GLY166, TYR167, ARG232, ILE235, ARG238, VAL239 and 4 more

Residues it binds most

TYR 1, ARG 1, THR 1, GLY 1, ILE 1, PRO 1, SER 1, VAL 1 (residue and the binding sites it lines).

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